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Summary
From birth through age two, an infant’s gut microbiome is reshaping itself almost daily. Today, this developing system faces more pressures than ever, as pregnancies and early childhoods are exposed to factors that may disrupt healthy microbiome formation and resilience. This program aims to identify how these growing early-life pressures may contribute to neurodevelopmental challenges including autism spectrum disorder. The goal is to develop scalable methods to protect, preserve and restore the maternal and infant gut microbiome – especially the core functions that guide neurodevelopment in key developmental windows during pregnancy and early infancy.