GRI-UK Conference 2026 This will be a landmark gathering for GRI families, scientists, and researchers — a weekend dedicated to learning, connection, and community. Hosted by the University of Edinburgh, the conference will be filled with informative sessions about GRI-related conditions, presentations on the latest research, and opportunities to meet and connect with GRI families. The full programme and speakers are listed below and available for download.Spaces are limited and early registration is encouraged. Registration closes 23.59 on Thursday 30 April 2026. Download the full programme and a glossary of scientific terms: Document GRI-UK Meeting Programme 14-16 May 2026 (2.74 MB / PDF) Document GRI-UK Glossary of Terms (288.97 KB / PDF) Programme Thursday 14 May 2026Location:Anatomy Lecture Theatre, Teviot Building, Old Medical Schoolwhat3words: ///judges.relate.froze Research presentations - Session 1 Time Event Speaker(s) Affiliation 12.30 Lunch available on arrival 13.15 Welcome address GRI-UK and David Wyllie 13.30 Calcium signalling and NMDA receptor variants Lonnie Wollmuth Stony Brook University, USA 14.00 sion trafficking and GRIN disorders Katherine Roche NIH, Bethesda, USA 14.30 Characterisation of disease-relevant GRIN1 variant mouse models Graham Collingridge University of Toronto, Canada 15.00 Coffee and tea break 15.30 Restoring inhibitory synapse plasticity in intellectual disability Derek Bowie McGill University, Canada 16.00 Characterisation of hippocampal function in a rat model of GRIN2B-related neurodevelopmental disorder Emma Wood Characterisation of hippocampal function in a rat model of GRIN2B-related neurodevelopmental disorder University of Edinburgh 16.30 - 18.00 Posters and drinks reception Friday 15 May 2026 Research Presentations - Session 2 Location:Anatomy Lecture Theatre, Teviot Building, Old Medical Schoolwhat3words: ///judges.relate.froze Time Event Speaker Affiliation 09.00 Coffee and tea on arrival 09.30 Truncating GRIN2B variants: molecular insights and behavioural deficits Hongjie Yuan Emory University, USA 10.00 Characterisation of tactile and pain phenotypes in a rat model of GRIN2B haploinsufficiency Carole Torsney University of Edinburgh 10.30 Structure and bi-functional role of a peripheral AMPA receptor auxiliary subunit Ingo Greger LMB Cambridge, UK 11.00 Mechanism and subunit-dependence of disease-causing Lurcher mutation in AMPA-type glutamate receptors Jelena Baranovic University of Edinburgh 11.30 - 11.45 Closing discussion Family Presentations - Session 3 Location:Hugh Robson Lecture Theatre, Hugh Robson Building, George Squarewhat3words: ///switch.remedy.onion Time Event Speaker(s) Affiliation 12.15 Lunch on arrival 13.15 Welcome address GRI-UK and David Wyllie 13.30 The global GRIN registry: advancing genotype-phenotype correlations and therapeutic insights Johannes Lemke and Maike Karnstedt University of Leipzig, Germany 14.05 Functional analysis of GRIN variants: how does it work and what does it tell us? Stephen Traynelis Emory University, USA 14.30 Participating in research trials Sameer Zuberi University of Glasgow 14.55 Coffee and tea break 15.25 Receptors, synapses and signalling in the brain David Wyllie University of Edinburgh 15.50 Probing the consequences of GRIN2 variants on signal transmission between neurons Andy Penn University of Sussex 16.15 Mila to Millions: a new era of individualised medicines Julia Vitarello Mila’s Miracle Foundation 16.40 Developing Investigational Radiprodil for Targeted Treatment of GRIN-Related Neurodevelopmental Disorder (GRIN-NDD) Bruce Leuchter, Hillary Savoie and Anne-Marie Li-Kwai-Cheung GRIN Therapeutics 17.05 - 17.20 Closing discussion Social Event - Ceilidh 18.45 Friday 15 May 2026, 18.45 to 21.00Binks Hall, 138-140 Pleasance, Edinburgh, EH8 9RRwhat3words: ///shine.rigid.fend Saturday 16 May 2026Location:Hugh Robson Lecture Theatre, Hugh Robson Building, George Squarewhat3words: ///switch.remedy.onion Family Presentations - Session 4 Time Event Speaker(s) Affiliation 09.30 Coffee and tea on arrival 10.00 Welcome Address GRI-UK and David Wyllie 10.10 GRI-UK: How we got here, who we’re here for, and where we’re going Alyson Koopman GRI-UK 10.25 The Global View: CureGRIN, the GRI Census and the 'How to Treat and Cure GRI Disorders Guide' Keith McArthur and Lauren Williams CureGRIN 10.40 GRIN Europe’s initiatives to advance research, patient care and family support Gilianne Nelissen GRIN Europe 10.55 Discussion/Q&A with GRI-UK, CureGRIN and GRIN Europe 11.05 The Dutch Brain Lab Facility: adult GRI patients as a window into natural history and trial outcome measures across the lifespan Danielle Veenma Erasmus MC, The Netherlands 11.30 Genes, Brains, and Breakthroughs: carer-centred accessible educational videos on neurodevelopmental conditions and therapy Narjes Rohani University of Oxford, UK 11.55 Loss- or gain-of function? Why we need to know and how we find out? Ian Coombs University College London, UK 12.20 Lunch Family Presentations - Session 5 Time Event Speaker(s) Affiliation 13.30 Understanding sensory processing in a rat model of GRIN2B haploinsufficiency Carole Torsney University of Edinburgh, UK 13.55 Characterisation of disease-relevant GRIN1 variant mouse models Graham Collingridge University of Toronto, Canada 14.20 An update on mouse models to study GRIN disorders Katherine Roche NIH, Bethesda, USA 14.45 Finding common ground in intellectual disability Derek Bowie McGill University, Canada 15.10 Coffee and tea break 15.45 Those beautiful but complicated NMDA receptors Lonnie Wollmuth Stony Brook University, USA 16.10 Sleep and brain activity in a rat model of GRIN2B disorder Alfredo Gonzalez-Sulser University of Edinburgh, UK 16.35 Convergence in neurodevelopmental disorders Peter Kind University of Edinburgh, UK 17.00 Closing discussion Social Event - Garden Party - 17.15 Saturday 16 May, 17:15 to 19:00George Square Gardens, George Square, Edinburghwhat3words: ///lower.views.gifts May 14 2026 - May 16 2026 GRI-UK Conference 2026 First ever GRI-UK Conference University of Edinburgh, central campus (see programme) Registration
GRI-UK Conference 2026 This will be a landmark gathering for GRI families, scientists, and researchers — a weekend dedicated to learning, connection, and community. Hosted by the University of Edinburgh, the conference will be filled with informative sessions about GRI-related conditions, presentations on the latest research, and opportunities to meet and connect with GRI families. The full programme and speakers are listed below and available for download.Spaces are limited and early registration is encouraged. Registration closes 23.59 on Thursday 30 April 2026. Download the full programme and a glossary of scientific terms: Document GRI-UK Meeting Programme 14-16 May 2026 (2.74 MB / PDF) Document GRI-UK Glossary of Terms (288.97 KB / PDF) Programme Thursday 14 May 2026Location:Anatomy Lecture Theatre, Teviot Building, Old Medical Schoolwhat3words: ///judges.relate.froze Research presentations - Session 1 Time Event Speaker(s) Affiliation 12.30 Lunch available on arrival 13.15 Welcome address GRI-UK and David Wyllie 13.30 Calcium signalling and NMDA receptor variants Lonnie Wollmuth Stony Brook University, USA 14.00 sion trafficking and GRIN disorders Katherine Roche NIH, Bethesda, USA 14.30 Characterisation of disease-relevant GRIN1 variant mouse models Graham Collingridge University of Toronto, Canada 15.00 Coffee and tea break 15.30 Restoring inhibitory synapse plasticity in intellectual disability Derek Bowie McGill University, Canada 16.00 Characterisation of hippocampal function in a rat model of GRIN2B-related neurodevelopmental disorder Emma Wood Characterisation of hippocampal function in a rat model of GRIN2B-related neurodevelopmental disorder University of Edinburgh 16.30 - 18.00 Posters and drinks reception Friday 15 May 2026 Research Presentations - Session 2 Location:Anatomy Lecture Theatre, Teviot Building, Old Medical Schoolwhat3words: ///judges.relate.froze Time Event Speaker Affiliation 09.00 Coffee and tea on arrival 09.30 Truncating GRIN2B variants: molecular insights and behavioural deficits Hongjie Yuan Emory University, USA 10.00 Characterisation of tactile and pain phenotypes in a rat model of GRIN2B haploinsufficiency Carole Torsney University of Edinburgh 10.30 Structure and bi-functional role of a peripheral AMPA receptor auxiliary subunit Ingo Greger LMB Cambridge, UK 11.00 Mechanism and subunit-dependence of disease-causing Lurcher mutation in AMPA-type glutamate receptors Jelena Baranovic University of Edinburgh 11.30 - 11.45 Closing discussion Family Presentations - Session 3 Location:Hugh Robson Lecture Theatre, Hugh Robson Building, George Squarewhat3words: ///switch.remedy.onion Time Event Speaker(s) Affiliation 12.15 Lunch on arrival 13.15 Welcome address GRI-UK and David Wyllie 13.30 The global GRIN registry: advancing genotype-phenotype correlations and therapeutic insights Johannes Lemke and Maike Karnstedt University of Leipzig, Germany 14.05 Functional analysis of GRIN variants: how does it work and what does it tell us? Stephen Traynelis Emory University, USA 14.30 Participating in research trials Sameer Zuberi University of Glasgow 14.55 Coffee and tea break 15.25 Receptors, synapses and signalling in the brain David Wyllie University of Edinburgh 15.50 Probing the consequences of GRIN2 variants on signal transmission between neurons Andy Penn University of Sussex 16.15 Mila to Millions: a new era of individualised medicines Julia Vitarello Mila’s Miracle Foundation 16.40 Developing Investigational Radiprodil for Targeted Treatment of GRIN-Related Neurodevelopmental Disorder (GRIN-NDD) Bruce Leuchter, Hillary Savoie and Anne-Marie Li-Kwai-Cheung GRIN Therapeutics 17.05 - 17.20 Closing discussion Social Event - Ceilidh 18.45 Friday 15 May 2026, 18.45 to 21.00Binks Hall, 138-140 Pleasance, Edinburgh, EH8 9RRwhat3words: ///shine.rigid.fend Saturday 16 May 2026Location:Hugh Robson Lecture Theatre, Hugh Robson Building, George Squarewhat3words: ///switch.remedy.onion Family Presentations - Session 4 Time Event Speaker(s) Affiliation 09.30 Coffee and tea on arrival 10.00 Welcome Address GRI-UK and David Wyllie 10.10 GRI-UK: How we got here, who we’re here for, and where we’re going Alyson Koopman GRI-UK 10.25 The Global View: CureGRIN, the GRI Census and the 'How to Treat and Cure GRI Disorders Guide' Keith McArthur and Lauren Williams CureGRIN 10.40 GRIN Europe’s initiatives to advance research, patient care and family support Gilianne Nelissen GRIN Europe 10.55 Discussion/Q&A with GRI-UK, CureGRIN and GRIN Europe 11.05 The Dutch Brain Lab Facility: adult GRI patients as a window into natural history and trial outcome measures across the lifespan Danielle Veenma Erasmus MC, The Netherlands 11.30 Genes, Brains, and Breakthroughs: carer-centred accessible educational videos on neurodevelopmental conditions and therapy Narjes Rohani University of Oxford, UK 11.55 Loss- or gain-of function? Why we need to know and how we find out? Ian Coombs University College London, UK 12.20 Lunch Family Presentations - Session 5 Time Event Speaker(s) Affiliation 13.30 Understanding sensory processing in a rat model of GRIN2B haploinsufficiency Carole Torsney University of Edinburgh, UK 13.55 Characterisation of disease-relevant GRIN1 variant mouse models Graham Collingridge University of Toronto, Canada 14.20 An update on mouse models to study GRIN disorders Katherine Roche NIH, Bethesda, USA 14.45 Finding common ground in intellectual disability Derek Bowie McGill University, Canada 15.10 Coffee and tea break 15.45 Those beautiful but complicated NMDA receptors Lonnie Wollmuth Stony Brook University, USA 16.10 Sleep and brain activity in a rat model of GRIN2B disorder Alfredo Gonzalez-Sulser University of Edinburgh, UK 16.35 Convergence in neurodevelopmental disorders Peter Kind University of Edinburgh, UK 17.00 Closing discussion Social Event - Garden Party - 17.15 Saturday 16 May, 17:15 to 19:00George Square Gardens, George Square, Edinburghwhat3words: ///lower.views.gifts May 14 2026 - May 16 2026 GRI-UK Conference 2026 First ever GRI-UK Conference University of Edinburgh, central campus (see programme) Registration
