Vascular Contributions to Dementia and Neurodegeneration

A four-year PhD programme funded by the British Heart Foundation and the UK Dementia Research Institute

British Heart Foundation and UK Dementia Research Institute Logos with Old college background

Applications open

The British Heart Foundation and UK Dementia Research Institute are funding a 4-year PhD programme across the Universities of Edinburgh, Oxford, Leicester and University College London, focused on Vascular Contributions to Dementia and Neurodegeneration. The programme will recruit 5 students per year, with the first intake in September 2026. 

Stipends and fees will be paid at the BHF rate, and additional research funds and travel costs will be available to host laboratories.

Strtucture

Students will spend the first year rotating across laboratories to gain training in a broad range of research techniques, before selecting a full research project and supervisor for the subsequent three years. Available projects span the full spectrum of research into vascular dementia and neurodegeneration. Potential supervisors and projects are listed below.

Eligibility

Applicants should have, or expect to obtain, at least an upper second-class degree in any area of Biological or Physical Sciences. Non-UK applicants may apply and, if successful, will receive the normal BHF stipend, but may be required to cover the international fees. 

Application process

To apply, please send a CV and a statement (maximum 2 pages) outlining your interest in the programme, and arrange for two referees to submit references to: neurophd@ucl.ac.uk. 

Please note that applicants are responsible for ensuring referees submit their references.

Please also specify in your application which university you would prefer to attend.

Shortlisted applicants will be invited to an online interview shortly after the deadline. The PhD programme will commence in September 2026.

Deadline for applications: Tuesday 14 April 2026

Contacts for further information

For further information, please contact one of the following university leads:

David Attwell, UCL, d.attwell@ucl.ac.uk

Jatinder Minhas, Leicester, jm591@leicester.ac.uk

Axel Montagne, Edinburgh, axel.montagne@ed.ac.uk

Sana Suri, Oxford, sana.suri@psych.ox.ac.uk

List of available projects

UCL

ProjectSupervisor
Cerebral blood flow and dementiaProf David Attwell,  Director of PhD Programme
CNS vascular pathology and regeneration, micoglia-blood vessel cross-talkProf Christiana Ruhrberg
Brain energy supply and demand in health and diseaseProf Catherine Hall
Control of cerebral blood flow, circulation and breathingProf Alexander Gourine
MRI of Cerebral PhysiologyProf Jack Wells
Oculomics - using the eye as a window to systemic health (with a particular focus on cardiovascular disease)Prof Pearse A Keane
Synapse degeneration in Alzheimer's diseaseProf Patricia C. Salinas
Personalised patient derived models of dementiaProfessor Selina Wray
Neuro-glia-immune interactions in neurodegenerationDr. Soyon Hong
Mitochondrial dynamics in CNS health and diseaseProf Josef Kittler
Neuroimaging to understand Parkinson's dementiaProf Rimona Weil
Cerebral small vessel disease, intracerebral haemorrhage, stroke, dementiaProf David Werring FMedSci
White matter blood flow and neurodegenerationProf Ken Smith, PhD

 

University of Edinburgh

ProjectPrimary Supervisor
Blood-brain barrier, vascular contribution to dementiaDr Axel Montagne,     Co-director
Large scale epidemiologyProf. William Whiteley
The role of astrocyte subtypes in bain function and dysfunctionDr. Philip Hasel
My lab investigates how astrocytes interact with the brain vasculature to understand how they contribute to healthy brain function and to the development of diseases that lead to dementia.Dr. Blanca Díaz Castro
Clinical epidemiology of stroke due to intracerebral haemorrhageProf. Rustam Al-Shahi Salman
Unraveling pathophysiological mechanisms of microvascular injury in cerebral amyloid angiopathyProf Susanne van Veluw
Oligo-vascular interactions and neuronal activity in small vessel disease and dementia.Dr. Rikesh Rajani
1. Understanding mechanisms of remyelination in Central Nervous System (CNS) repair. 2. Manipulating remyelination to generate target compounds to promote CNS repair.3. Understanding mechanisms of cerebral small vessel disease (SVD).Prof. Anna Williams
Invesitgating why ischaemic stroke causes cognitive decline and dementia using human tissue (CogFAST) and mouse models with variety of approaches ie MRI, behaviour in mouse to assess cognition, sn/scRNA seq, spatial transcriptomics; with a focus on glial cell and white matter changesDr. Jill Fowler
Vascular-immune interactions and link to VCIDProf. Karen Horsburgh
Neuroimmune mechanisms in cerebrovascular disease and dementiaDr. Barry McColl
The neuropathology of human cerebrovascular disease and neurodegenerative dsiordersProf. Colin Smith

University of Leicester

Project Supervisor
Cerebrovascular haemodynamics, cerebrovascular reactivity in acute intracerebral haemorrhage, lacunar stroke syndromes and cerebral small vessel disease.

Dr. Jatinder Minhas,

Co-director

Non-invasive imaging techniques to study vascular pathophysiology  and the development of Alzheimer’s disease, mild cognitive impairment, vascular and post-stroke cognitive impairment, and related disorders of ageing such as delirium and depression.Dr. Lucy Beishon
Non-invasive retinal imaging to gain insights into retinal and systemic diseases at the individual and population level. Eye tracking in retinal and vascular neurological disorders. Dr. Mervyn Thomas

University of Oxford

ProjectSupervisor
Imaging vascular risk for dementia

Prof Sana Suri,

Co-director

Neurovascular unit and microfludic cell culture systemsDr. Paul Holloway
Role of blood-brain barrier in neurodegeneration and CNS injuriesDr. Mootaz Salman
Clinical stroke epidemiology in young adultsDr. Linxin Li
Lipid metabolism and dementiaDr. Hugo Fernandes
Brain imaging in dementia and neurodegenerationProf Ludovica Griffanti
Brain blood flow imagingProf Thomas Okell
Multiomic analysis of dementia and neurodegenerationDr. Laura Winchester
Biofluid markers of metabolic changes in Alzheimer's DiseaseDr. Becky Carlyle
Physiological assessment using MRIProf. Peter Jezzard
Single cell omics & stem cell models in vascular dementiaProf Zameel Cader 
Post-stroke vascular dysfunctionProf  Yvonne Couch
Genetic Epidemiology of Alzheimer's diseaseProf Dr Cornelia Van Duijn