Vascular Contributions to Dementia and Neurodegeneration

A four-year PhD programme funded by the British Heart Foundation and the UK Dementia Research Institute

British Heart Foundation and UK Dementia Research Institute Logos with Old college background

PhD programme details

The British Heart Foundation and UK Dementia Research Institute are funding a 4-year PhD programme across the Universities of Edinburgh, Oxford, Leicester and University College London, focused on Vascular Contributions to Dementia and Neurodegeneration. The programme will recruit 5 students per year, with the next intake in September 2027. 

Stipends and fees will be paid at the BHF rate, and additional research funds and travel costs will be available to host laboratories.

Strtucture

Students will spend the first year rotating across laboratories to gain training in a broad range of research techniques, before selecting a full research project and supervisor for the subsequent three years. Available projects span the full spectrum of research into vascular dementia and neurodegeneration. Potential supervisors and projects are listed below.

Eligibility

Applicants should have, or expect to obtain, at least an upper second-class degree in any area of Biological or Physical Sciences. Non-UK applicants may apply and, if successful, will receive the normal BHF stipend, but may be required to cover the international fees. 

Application process

Applications can be emailed to neurophd@ucl.ac.uk between 1st November - 15th December 2026. Interviews will be online in January. The PhD programme will start in September 2027. 

To apply, please send a CV (maximum 2 pages) including research experience and the mean percentage grade obtained in your degree(s), and a statement (maximum 1 page) outlining how your research interest matches the programme and stating your goals for the PhD. Then arrange for two referees to send references to: neurophd@ucl.ac.uk by 20th December 2026.  

Please note that applicants are responsible for ensuring referees submit their references.

Please also specify in your application which university you would prefer to attend.

Contacts and links for further information

For further information, please contact one of the following university leads:

David Attwell, UCL, d.attwell@ucl.ac.uk

Jatinder Minhas, Leicester, jm591@leicester.ac.uk

Axel Montagne, Edinburgh, axel.montagne@ed.ac.uk

Sana Suri, Oxford, sana.suri@psych.ox.ac.uk

Further information on the PhD Programme will appear on the the programme's UCL website.

Participating supervisors and their research areas

 

UCL

Research areaSupervisor
Cerebral blood flow and dementiaProf David Attwell, Director of PhD Programme
CNS vascular pathology and regeneration, micoglia-blood vessel cross-talkProf Christiana Ruhrberg
Brain energy supply and demand in health and diseaseProf Catherine Hall
AIS and node of Ranvier disruption in Alzheimer’s diseaseDr Jonathan Lezmy
Oculomics - using the eye as a window to systemic health (with a particular focus on cardiovascular disease)Prof Pearse A Keane
Personalised patient derived models of dementiaProfessor Selina Wray
Neuro-glia-immune interactions in neurodegenerationDr. Soyon Hong
Mitochondrial dynamics in CNS health and diseaseProf Josef Kittler
Neuroimaging to understand Parkinson's dementiaProf Rimona Weil
Cerebral small vessel disease, intracerebral haemorrhage, stroke, dementiaProf David Werring FMedSci
The vascular, immune and myelin systems in human longevity, neurodegeneration and inflammatory diseaseDr Dervis Salih

 

University of Edinburgh

Research areaPrimary Supervisor
Blood-brain barrier, vascular contribution to dementiaDr Axel Montagne, Co-director
Large scale epidemiologyProf. William Whiteley
The role of astrocyte subtypes in brain function and dysfunctionDr. Philip Hasel
How astrocytes interact with the brain vasculature to understand how they contribute to healthy brain function and to the development of diseases that lead to dementia.Dr. Blanca Díaz Castro
Clinical epidemiology of stroke due to intracerebral haemorrhageProf. Rustam Al-Shahi Salman
Unraveling pathophysiological mechanisms of microvascular injury in cerebral amyloid angiopathyProf Susanne van Veluw
Oligo-vascular interactions and neuronal activity in small vessel disease and dementia.Dr. Rikesh Rajani
1. Understanding mechanisms of remyelination in Central Nervous System (CNS) repair. 
2. Manipulating remyelination to generate target compounds to promote CNS repair.
3. Understanding mechanisms of cerebral small vessel disease (SVD).
Prof. Anna Williams
Investigating why ischaemic stroke causes cognitive decline and dementia using human tissue (CogFAST) and mouse models with variety of approaches i.e. MRI, behaviour in mouse to assess cognition, sn/scRNA seq, spatial transcriptomics; with a focus on glial cell and white matter changesDr. Jill Fowler
Neural circuit dysfunction, synaptic transmission, and cognitive processesDr Jian Gan 
Neuroimmune mechanisms in cerebrovascular disease and dementiaDr. Barry McColl
The neuropathology of human cerebrovascular disease and neurodegenerative disordersProf. Colin Smith

 

University of Leicester

Research area Supervisor
Cerebrovascular haemodynamics, cerebrovascular reactivity in acute intracerebral haemorrhage, lacunar stroke syndromes and cerebral small vessel disease.Dr. Jatinder Minhas, Co-director
Cerebral haemodynamics in strokeProf Ronney Panerai
Non-invasive retinal imaging to gain insights into retinal and systemic diseases at the individual and population level. Eye tracking in retinal and vascular neurological disorders. Dr. Mervyn Thomas
Haemodynamic responses during visual tasks Dr David Souto 
Vascular endothelial cell ageing Prof Veryan Codd

 

University of Oxford

Research areaSupervisor
Imaging vascular risk for dementiaProf Sana Suri, Co-director
Neurovascular unit and microfludic cell culture systemsDr. Paul Holloway
Role of blood-brain barrier in neurodegeneration and CNS injuriesDr. Mootaz Salman
Clinical stroke epidemiology in young adultsDr. Linxin Li
Lipid metabolism and dementiaDr. Hugo Fernandes
Brain imaging in dementia and neurodegenerationProf Ludovica Griffanti
Brain blood flow imagingProf Thomas Okell
Multiomic analysis of dementia and neurodegenerationDr. Laura Winchester
Biofluid markers of metabolic changes in Alzheimer's DiseaseDr. Becky Carlyle
Physiological assessment using MRIProf. Peter Jezzard
Single cell omics & stem cell models in vascular dementiaProf Zameel Cader 
Alcohol, white matter hyperintensities and dementia Dr Anya Topiwala 
Single cell omics & stem cell models in vascular dementiaProf Zameel Cader MRCP DPhil
Neural networks as models for cognitive symptoms in cerebrovascular diseaseProf Sanjay Manohar