The hippocampus is a region in the brain that is critical for learning and memory, and one of the first regions affected in Alzheimer’s disease. The proper functioning of the hippocampus relies on the communication between specialized types of brain cells (neurons). In particular, different types of inhibitory neurons control or modulate the activity of other neurons, and so are critical in memory function. My laboratory is interested in how changes to inhibitory cells in the hippocampus can alter circuit function in diseases that affect memory, such as Alzheimer's disease.