Research summary

I am an academic neurosurgical trainee and am passionate about trying to find solutions to the consequences of acute brain injury. I combine preclinical and clinical methodologies to understand processes of of disease that are harmful or protective in patients and aim to use these to develop new treatments or optimise current management strategies.

Current interests

I use in vitro and in vivo models of brain haemorrhage to investigate how microglia and recruited peripheral immune cells, sculpt astrocyte and neuronal responses to brain haemorrhage. Using brain tissue and clinical data of patients with brain haemorrhage, I aim to identify mechanisms of injury and neuroprotection that are conserved in patients and harness them therapeutically. This work builds on that of my PhD, supervised by Prof. Giles Hardingham, Dr. Barry McColl and Prof. Rustam Salman and funded by the Wellcome Trust and supported by the UK Dementia Research Institute.